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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKNK2
All Species:
16.67
Human Site:
S27
Identified Species:
33.33
UniProt:
Q9HBH9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBH9
NP_060042.2
465
51875
S27
N
P
F
E
L
A
F
S
L
D
Q
P
D
H
G
Chimpanzee
Pan troglodytes
XP_512248
805
84821
A24
L
A
W
K
A
A
P
A
L
P
H
P
P
P
G
Rhesus Macaque
Macaca mulatta
XP_001117579
489
54064
S51
N
P
F
E
L
A
F
S
L
D
Q
P
H
H
G
Dog
Lupus familis
XP_855041
1044
109683
S616
N
P
F
E
L
A
F
S
L
D
Q
T
P
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDB0
459
51614
S27
N
P
F
E
L
A
F
S
L
D
L
A
Q
H
R
Rat
Rattus norvegicus
Q5U2N4
459
51555
T27
N
P
F
E
L
A
F
T
L
D
P
A
Q
H
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235171
508
56331
W76
L
P
M
P
P
T
C
W
M
E
A
G
Q
N
T
Frog
Xenopus laevis
Q6P431
467
52653
E27
N
P
F
D
A
A
Y
E
M
E
A
R
N
M
E
Zebra Danio
Brachydanio rerio
NP_997888
472
52923
F27
N
P
F
K
T
D
E
F
I
D
S
D
S
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731624
1090
123424
S21
E
D
V
S
G
N
E
S
S
E
A
P
N
M
T
Honey Bee
Apis mellifera
XP_395927
516
58135
S21
T
V
N
S
T
G
E
S
M
S
A
V
Q
A
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779905
511
56921
A53
M
P
D
C
K
A
T
A
E
N
Y
A
N
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.8
92.4
34.6
N.A.
92.6
92.6
N.A.
N.A.
60.8
76.8
73.3
N.A.
24
49.8
N.A.
48.7
Protein Similarity:
100
48.5
93.4
36.8
N.A.
95.2
95.2
N.A.
N.A.
73
87.7
84.5
N.A.
31
66.6
N.A.
64.5
P-Site Identity:
100
26.6
93.3
80
N.A.
73.3
73.3
N.A.
N.A.
6.6
26.6
33.3
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
46.6
93.3
80
N.A.
73.3
80
N.A.
N.A.
26.6
60
46.6
N.A.
26.6
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
17
67
0
17
0
0
34
25
0
9
0
% A
% Cys:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
9
0
9
0
0
0
50
0
9
9
0
0
% D
% Glu:
9
0
0
42
0
0
25
9
9
25
0
0
0
0
9
% E
% Phe:
0
0
59
0
0
0
42
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
9
0
0
0
0
0
9
0
0
42
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
9
42
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
17
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
17
0
0
0
42
0
0
0
50
0
9
0
0
0
9
% L
% Met:
9
0
9
0
0
0
0
0
25
0
0
0
0
17
0
% M
% Asn:
59
0
9
0
0
9
0
0
0
9
0
0
25
17
9
% N
% Pro:
0
75
0
9
9
0
9
0
0
9
9
34
17
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
25
0
34
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
17
% R
% Ser:
0
0
0
17
0
0
0
50
9
9
9
0
9
0
0
% S
% Thr:
9
0
0
0
17
9
9
9
0
0
0
9
0
0
17
% T
% Val:
0
9
9
0
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _